Americans are dying at startling rates, not only from COVID-19 but also its reverberating socioeconomic effects: massive unemployment, food insecurity, social isolation, and stress-related increases in smoking, alcohol use, opioid use, and suicide. To save lives, we need scientific advances, not only in biomedicine—virology, vaccine development, and critical care—but also in interventions that the address social determinants of health. Read the Full Article.