Element E
Advance Clinical Translatable Science by Addressing Roadblocks
Element E has the goal to advance clinical translational science (CTS) through innovative, highly-translatable research projects that address significant roadblocks in the field. Specifically, we will identify and nurture CTS projects aimed at improving dissemination and implementation of evidence-based interventions. We will leverage the resources of NJ ACTS to ensure the success of these high-impact CTS projects and disseminate findings broadly to improve clinical care and population health in New Jersey.
2025 Element E RFA
This RFA solicits innovative projects that address significant roadblocks in clinical and translational science (CTS). Faculty investigators at Rutgers University, Princeton University, New Jersey Institute of Technology, and the RWJBarnabas Health System are eligible to apply.
Projects should:
- Focus on strategies and/or innovations to overcome truly significant challenges in clinical and translational research
- Improve dissemination and/or implementation of evidence-based interventions
- Address a translational research question in a particular disease or intervention context, but provide insights or innovations that are generalizable across different diseases and/or translational research projects
- Increase efficiency and/or effectiveness of research translation
- Budget up to $162,500 in direct costs per year for up to two years.
Key Dates:
RFA Release: August 4, 2025
Letter of Intent Deadline: September 15, 2025 (LOI Form Link)
Notification of Projects Selected for Full Proposals: Early October 2025
Full Proposal Deadline: November 21, 2025 by 5:00 PM EST
Award Notification: January 2026
Earliest State Date: May 1, 2026
Project E1 - Implementation of a novel genetic services model to enhance patient care
- Recent genetic advances led to dramatic increases in genetic testing availability
- The number of patients referred for genetic services has grown faster than the number of MD clinical geneticists
- Wait times are 6-12 months for an initial appointment, which may perpetuate health disparities
Project E2 - Translating evidence on opioid overdose prevention into practice
Applying translational science to strategies and outcomes for opioid use disorder (OUD) treatment engagement among overdose survivors
- Emergency departments represent important, novel touchpoints for addressing opioid overdoses
- However, uptake of evidence-based treatment (i.e., buprenorphine) is low in emergency departments
- There are knowledge gaps on best practices for increasing treatment uptake in emergency departments
Element E Leadership
Emily S. Barrett, PhD
George G. Rhoads Endowed Legacy Professor of Epidemiology
Vice Chair, Department of Biostatistics and Epidemiology
Deputy Director, Rutgers Center for Environmental Exposures and Disease (CEED)
Co-Director of Population Exposures and Outcomes Research Core
Director, Maternal-Child Environmental Health Lab
esb104@eohsi.rutgers.edu
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